TL;DR: The use of brown alga (Bifurcaria bifurcata) while in the biosynthesis of copper oxide nanoparticles of dimensions five–45 nm is described for The 1st time and these nanoparticles were being discovered to exhibit large antibacterial activity against two distinct strains of bacteria. The positioning is protected. The https:// makes https://www.directivepublications.org/journal-of-applied-nanoscience/